https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38204 Wed 18 Aug 2021 09:53:13 AEST ]]> Natural products in the management of obesity: Fundamental mechanisms and pharmacotherapy https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53698 Wed 10 Jan 2024 10:49:33 AEDT ]]> Antibacterial and antioxidant potential of biosynthesized copper nanoparticles mediated through Cissus arnotiana plant extract https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36822 Cissus arnotiana and evaluated their antibacterial activity against gram negative and gram positive bacteria. The morphology and characterization of the synthesized CuNPs were studied and done using UV-Visible spectroscopy at a wavelength range of 350–380 nm. XRD studies were performed for analyzing the crystalline nature; SEM and TEM for evaluating the spherical shape within the size range of 60–90 nm and AFM was performed to check the surface roughness. The biosynthesized CuNPs showed better antibacterial activity against the gram-negative bacteria, E. coli with an inhibition zone of 22.20 ± 0.16 mm at 75 μg/ml. The antioxidant property observed was comparatively equal with the standard antioxidant agent ascorbic acid at a maximum concentration of 40 μg/ ml. This is the first study reported on C. arnotiana mediated biosynthesis of copper nanoparticles, where we believe that the findings can pave way for a new direction in the field of nanotechnology and nanomedicine where there is a significant potential for antibacterial and antioxidant activities. We predict that, these could lead to an exponential increase in the field of biomedical applications, with the utilization of green synthesized CuNPs, due to its remarkable properties. The highest antibacterial property was observed with gram-negative strains mainly, E. coli, due to its thin peptidoglycan layer and electrostatic interactions between the bacterial cell wall and CuNPs surfaces. Hence, CuNPs can be potent therapeutic agents in several biomedical applications, which are yet to be explored in the near future.]]> Wed 08 Jul 2020 13:55:41 AEST ]]> The potential of siRNA based drug delivery in respiratory disorders: recent advances and progress https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44965 Tue 25 Oct 2022 13:46:05 AEDT ]]> Calcium sensing receptor hyperactivation through viral envelop protein E of SARS CoV2: A novel target for cardio-renal damage in COVID-19 infection https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53385 Thu 23 Nov 2023 12:55:23 AEDT ]]> Emerging trends in the novel drug delivery approaches for the treatment of lung cancer https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36704 Thu 09 Dec 2021 11:02:25 AEDT ]]> Oligonucleotide therapy: an emerging focus area for drug delivery in chronic inflammatory respiratory diseases https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48492 Mon 20 Mar 2023 12:13:02 AEDT ]]> Interactions between microbiome and lungs: paving new paths for microbiome based bio-engineered drug delivery systems in chronic respiratory diseases https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37006 Fri 22 Apr 2022 10:21:09 AEST ]]>